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Subtyping of Shiga toxin 2 variants in human-derived Shiga toxin-producing Escherichia coli strains isolated in Japan.

FEMS immunology and medical microbiology - 13 Dec 2002

Nakao Hiroshi, Kimura Kouichi, Murakami Hiroyuki, Maruyama Tsutomu, Takeda Tae

Abstract excerpt

Shiga toxin 2 (Stx2) variants have been found to exhibit not only antigenic divergence, but also differences in toxicity for tissue culture cells and animals. To clarify whether all or just a subset of Stx2 variants are important for the virulence of Shiga toxin-producing Escherichia coli, we designed PCR primers to detect and type all reported variants. We classified them into four groups according to the...

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PMID: 12443829
DOI: 10.1111/j.1574-695X.2002.tb00636.x

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