Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct patterns of chromosomal losses in clinically synchronous and asynchronous bilateral renal cell carcinoma.

The Journal of urology - 1 Dec 2002

Kito Hiroki, Suzuki Hiroshi, Igarashi Tatsou, Tobe Toyofusa, Mizoguchi Ken'ichi, Kamiya Naoto, Ichikawa Tomohiko, Ito Haruo

Abstract excerpt

PURPOSE: Bilateral renal cell carcinoma has been reported to occur in 1% to 4% of patients with renal cancer. However, whether bilateral renal cell carcinoma involves metastatic lesions of the contralateral kidney or develops as simultaneous primary tumors remains unclear to date. Thus, we investigated chromosomal losses and von Hippel-Lindau (VHL) gene abnormalities in bilateral tumors from patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Clone Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Ligases

Share to Loss of Heterozygosity

Share to Neoplasms, Multiple Primary

Share to Ubiquitin-Protein Ligases

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 12442000
DOI: 10.1016/S0022-5347(05)64234-6

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct patterns of chromosomal losses in clinically synchronous and asynchronous bilateral renal cell carcinoma.PMID 12442000Read ↗

Independent Tumor Origin in Two Cases of Synchronous Bilateral Clear Cell Renal Cell Carcinoma.Semantic proximity Read ↗

Differential VHL Mutation Patterns in Bilateral Clear Cell RCC Distinguishes Between Independent Primary Tumors and Contralateral Metastatic Disease.Semantic proximity Read ↗

Genetic identification of bilateral primary or metastatic nonpapillary renal cell carcinoma.Semantic proximity Read ↗

Risk of bilateral renal cell cancer.Semantic proximity Read ↗

Identification of somatic mutations in the von Hippel-Lindau (VHL) gene in a patient with renal cell carcinoma.Semantic proximity Read ↗

X chromosome inactivation and microsatellite instability in early and advanced bilateral ovarian carcinomas.Semantic proximity Read ↗

Clonal analysis of bilateral breast cancer.Semantic proximity Read ↗

Clonal analysis of bilateral mammary carcinomas by clinical evaluation and partial allelotyping.Semantic proximity Read ↗

Molecular study of clonality in multifocal and bilateral breast tumors.Semantic proximity Read ↗

Cytogenetic heterogeneity and clonal evolution in synchronous bilateral breast carcinomas and their lymph node metastases from a male patient without any detectable BRCA2 germline mutation.Semantic proximity Read ↗

Concordance of allelic imbalance profiles in synchronous and metachronous bilateral breast carcinomasSemantic proximity Read ↗

Genotypic divergence precedes clinical dissemination in a case of synchronous bilateral B-cell malignant lymphoma of the testes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.