Article
Clonal analysis of bilateral breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 1996
Shibata A, Tsai Y C, Press M F, Henderson B E, Jones P A, Ross R K
Abstract excerpt
Forty-nine pairs of bilateral breast tumors (41 synchronous and 8 asynchronous cases) were examined for X-chromosome inactivation status and p53 mutations to address the issue of their clonality. Among 12 cases that were informative for the trinucleotide repeat polymorphism in exon 1 of the androgen receptor gene on the X chromosome, 3 cases were found to have different alleles of the locus inactivated in the...
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