Article
X chromosome inactivation and microsatellite instability in early and advanced bilateral ovarian carcinomas.
Cancer research - 1 Nov 1995
Park T W, Felix J C, Wright T C
Abstract excerpt
Ovarian carcinoma can arise synchronously from multiple independent sites and metastasize widely. Therefore, it is frequently unclear whether bilateral tumors represent two independent primaries or one primary and a metastasis. We have used X chromosome inactivation of the androgen receptor gene and microsatellite instability at four chromosomal loci to evaluate the clonal origin of 39 bilateral ovarian...
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