Article
Association of (-)786T-C mutation of endothelial nitric oxide synthase gene with insulin resistance.
Diabetologia - 1 Nov 2002
Ohtoshi K, Yamasaki Y, Gorogawa S, Hayaishi-Okano R, Node K, Matsuhisa M, Kajimoto Y, Hori M
Abstract excerpt
AIMS/HYPOTHESIS: Endothelial derived nitric oxide synthase ( eNOS) gene polymorphisms affect eNOS activity and are associated with abnormal vasomotility and impaired local blood flow. A decrease in local blood flow has been reported to cause insulin resistance. The aim of this study was to examine a possible association of two eNOS polymorphisms, Glu298Asp (G894T) in exon 7 and (-)786T-C mutation with insulin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.