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Article

Postantibiotic effect and delay of regrowth in strains carrying mutations that save proteins or RNA.

Antimicrobial agents and chemotherapy - 1 Dec 2002

Dolcino Marzia, Zoratti Alberto, Debbia Eugenio A, Schito Gian Carlo, Marchese Anna

Abstract excerpt

The postantibiotic effect (PAE) values found for proteinase-defective (Lon(-)) Escherichia coli and RNase-defective E. coli exposed to antibiotics were reduced (31 to 60% and 35 to 50%, respectively) in comparison with the control (AB1157), and in the recA13 mutant these values were about 0.4 h with all drugs. Nalidixic acid, under anaerobic conditions, induced no PAE (0 to 0.1 h) in AB1157. A delay in regrowth...

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Identifiers

PMID: 12435717
DOI: 10.1128/AAC.46.12.4022-4025.2002
PMCID: PMC132785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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