Article
The balance between different peptidoglycan precursors determines whether Escherichia coli cells will elongate or divide.
Journal of bacteriology - 1 Dec 1990
Begg K J, Takasuga A, Edwards D H, Dewar S J, Spratt B G, Adachi H, Ohta T, Matsuzawa H, Donachie W D
Abstract excerpt
The rodA(Sui) mutation allows cell division to take place at 42 degrees C in ftsI23 mutant cells, which produce a thermolabile penicillin-binding protein 3 (PBP3, the septation-specific peptidoglycan transpeptidase). We show here that the mutation in rodA is a single-base change from a glutamine to a chain termination (amber) codon, and that an amber suppressor (supE) present in the strain restores the ability to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.