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Article

High resolution crystal structures of human Rab5a and five mutants with substitutions in the catalytically important phosphate-binding loop.

The Journal of biological chemistry - 24 Jan 2003

Zhu Guangyu, Liu Jian, Terzyan Simon, Zhai Peng, Li Guangpu, Zhang Xuejun C

Abstract excerpt

GTPase domain crystal structures of Rab5a wild type and five variants with mutations in the phosphate-binding loop are reported here at resolutions up to 1.5 A. Of particular interest, the A30P mutant was crystallized in complexes with GDP, GDP+AlF(3), and authentic GTP, respectively. The other v...

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Identifiers

PMID: 12433916
DOI: 10.1074/jbc.M211042200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12433916-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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