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Article

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.

Blood - 1 Apr 2003

Brenchley Jason M, Karandikar Nitin J, Betts Michael R, Ambrozak David R, Hill Brenna J, Crotty Laura E, Casazza Joseph P, Kuruppu Janaki, Migueles Stephen A, Connors Mark, Roederer Mario, Douek Daniel C, Koup Richard A

Abstract excerpt

Virus-specific CD8(+) T-cell responses play a pivotal role in limiting viral replication. Alterations in these responses, such as decreased cytolytic function, inappropriate maturation, and limited proliferative ability could reduce their ability to control viral replication. Here, we report on t...

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Source

Identifiers

PMID: 12433688
DOI: 10.1182/blood-2002-07-2103

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12433688-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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