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Article

The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry.

Nature - 14 Nov 2002

Zhong Haining, Molday Laurie L, Molday Robert S, Yau King-Wai

Abstract excerpt

Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions. These channels are tetramers and in their native forms are composed of A and B subunits, with a stoichiometry thought to be 2A:2B (refs 6, 7). Here we report the identification of a leucine-zipper-homology domain named CLZ (for carboxy-terminal leucine zipper). This domain is present in the distal C terminus of CNG channel...

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Identifiers

PMID: 12432397
DOI: 10.1038/nature01201
PMCID: PMC2877395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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