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Article

Metabolic network structure determines key aspects of functionality and regulation.

Nature - 14 Nov 2002

Stelling Jörg, Klamt Steffen, Bettenbrock Katja, Schuster Stefan, Gilles Ernst Dieter

Abstract excerpt

The relationship between structure, function and regulation in complex cellular networks is a still largely open question. Systems biology aims to explain this relationship by combining experimental and theoretical approaches. Current theories have various strengths and shortcomings in providing an integrated, predictive description of cellular networks. Specifically, dynamic mathematical modelling of large-scale...

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PMID: 12432396
DOI: 10.1038/nature01166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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