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Article

Interaction of periplakin and envoplakin with intermediate filaments

14 Nov 2002

Abstract excerpt

Periplakin is a component of desmosomes and the epidermal cornified envelope. Its N-terminal domain interacts with the plasma membrane; it heterodimerises with envoplakin via its rod domain; and its C-terminus interacts with intermediate filaments. Periplakin has the shortest C-terminus of the plakin family, comprising only the linker domain found in all conventional plakins. By transient transfection of COS7...

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Identifiers

PMID: 12432088
DOI: 10.1242/jcs.00191

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Related research

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Research trail→

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Interaction of periplakin and envoplakin with intermediate filamentsPMID 12432088Read ↗

Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentinSemantic proximity Read ↗

Periplakin Gene Targeting Reveals a Constituent of the Cornified Cell Envelope Dispensable for Normal Mouse DevelopmentSemantic proximity Read ↗

Cytolinker cross-talk: Periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migrationSemantic proximity Read ↗

Molecular mechanism of intermediate filament recognition by plakin proteins.Semantic proximity Read ↗

Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of the epidermal cornified envelope.Semantic proximity Read ↗

Interaction of the Bullous Pemphigoid Antigen 1 (BP230) and Desmoplakin with Intermediate Filaments Is Mediated by Distinct Sequences within Their COOH TerminusSemantic proximity Read ↗

Characterization of Periphilin, a Widespread, Highly Insoluble Nuclear Protein and Potential Constituent of the Keratinocyte Cornified EnvelopeSemantic proximity Read ↗

Binding of protein kinase B to the plakin family member periplakin.Semantic proximity Read ↗

Periplakin and envoplakin are target antigens in canine and human paraneoplastic pemphigusSemantic proximity Read ↗

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.Semantic proximity Read ↗

Epiplakin, a Novel Member of the Plakin Family Originally Identified as a 450-kDa Human Epidermal AutoantigenSemantic proximity Read ↗

Paraneoplastic Pemphigus Sera React Strongly with Multiple Epitopes on the Various Regions of Envoplakin and Periplakin, Except for the C-Terminal Homologous Domain of PeriplakinSemantic proximity Read ↗

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