Article
Increased frequency of interleukin-1beta-511T allele in patients with temporal lobe epilepsy, hippocampal sclerosis, and prolonged febrile convulsion.
Epilepsia - 1 Jun 2003
Kanemoto Kousuke, Kawasaki Jun, Yuasa Shoji, Kumaki Testuo, Tomohiro Oshima, Kaji Ryuji, Nishimura Masataka
Abstract excerpt
PURPOSE: To confirm the high frequency of interleukin (IL)-1beta-511T allele occurrence in patients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS), with special attention given to the impact of prolonged febrile convulsions (PFCs) on IL-1beta genotype distribution. METHODS: Patients with evidence of unilateral HS on magnetic resonance (MR) images were chosen as study subjects (TLE+HS; n = 66)....
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