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Article

Genetic susceptibility to simple febrile seizures: interleukin-1beta promoter polymorphisms are associated with sporadic cases.

Neuroscience letters - 26 Aug 2005

Kira Ryutaro, Torisu Hiroyuki, Takemoto Megumi, Nomura Akihiko, Sakai Yasunari, Sanefuji Masafumi, Sakamoto Kanji, Matsumoto Shigetaka, Gondo Kenjiro, Hara Toshiro

Abstract excerpt

Febrile seizures (FSs) are the commonest form of convulsions. A genetic predisposition to FSs is known, based on family studies, twin studies, and complex segregation analysis. Simple FSs may be more homogenous in their clinical manifestations, and show better agreement with the multifactorial inheritance theory than the complex type. Interleukin-1 (IL-1) beta is one of the pro-inflammatory cytokines that are...

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PMID: 15916853
DOI: 10.1016/j.neulet.2005.04.097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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