Article
Lack of association between an interleukin 1 beta (IL-1beta) gene variation and refractory temporal lobe epilepsy.
Epilepsia - 1 Jun 2001
Buono R J, Ferraro T N, O'Connor M J, Sperling M R, Ryan S G, Scattergood T, Mulholland N, Gilmore J, Lohoff F W, Berrettini W H
Abstract excerpt
PURPOSE: We attempted to confirm recent findings of Kanemoto et al. that demonstrated a positive association (p < 0.017) between a polymorphism in the promoter region of the interleukin 1-beta (IL-1beta) gene and the clinical phenotype of temporal lobe epilepsy with hippocampal sclerosis (TLE+HS). METHODS: We determined the frequency of this polymorphism in a group of 61 TLE+HS patients of European ancestry and...
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