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Gene Expression Profiling in AGS Cells Stimulated with<i>Helicobacter pylori</i>Isogenic Strains (<i>cagA</i>Positive or<i>cagA</i>Negative)

1 Feb 2002

Abstract excerpt

To study host response to CagA, human gastric cancer cell line AGS was infected with a Helicobacter pylori type I wild-type or isogenic cagA-negative mutant. Differentially expressed genes were identified using cDNA array technology. By Northern blotting, downregulation of focal adhesion kinase and upregulation of LIM kinase mRNA in the presence of CagA were clearly verified. Furthermore, upregulation of LIM...

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PMID: 11796637
DOI: 10.1128/iai.70.2.988-992.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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