Article
Testicular carcinoma and HLA Class II genes.
Cancer - 1 Nov 2002
Sonneveld Dirk J A, Lutke Holzik Martijn F, Nolte Ilja M, Sleijfer Dirk Th, van der Graaf Winette T A, Bruinenberg Marcel, Sijmons Rolf H, Hoekstra Harald J, Te Meerman Gerard J
Abstract excerpt
BACKGROUND: The association with histocompatibility antigens (HLA), in particular Class II genes (DQB1, DRB1), has recently been suggested to be one of the genetic factors involved in testicular germ cell tumor (TGCT) development. The current study, which uses genotyping of microsatellite markers, was designed to replicate previous associations. METHODS: In 151 patients, along with controls comprising parents or...
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