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Article

Positional cloning of an obesity/diabetes susceptibility gene(s) on chromosome 11 in Pima Indians.

Annals of the New York Academy of Sciences - 1 Jun 2002

Baier Leslie, Kovacs Peter, Wiedrich Christopher, Cray Kimberly, Schemidt Amy, Shen Gong-Qing, Sutherland Jeffrey, Thuillez Pamela, Muller Yunhua Li, Traurig Michael, Bogardus Clifton

Abstract excerpt

Prior results from our genomic scan in Pima Indians indicated an obesity locus in a region on chromosome 11q23-24 that was also linked to diabetes. Bivariate linkage analysis for the combined phenotype "diabesity" gave the strongest evidence for linkage (LOD = 5.2). Our aim is to positionally clone the gene(s) responsible for the linkage. Linkage disequilibrium mapping is being used to narrow the chromosomal...

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Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Indians, North American

Share to Linkage Disequilibrium

Share to Obesity

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 12079853
DOI: 10.1111/j.1749-6632.2002.tb04281.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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