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Article

Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney.

Development (Cambridge, England) - 1 Nov 2002

Yu Jing, Carroll Thomas J, McMahon Andrew P

Abstract excerpt

Signaling by the ureteric bud epithelium is essential for survival, proliferation and differentiation of the metanephric mesenchyme during kidney development. Most studies that have addressed ureteric signaling have focused on the proximal, branching, ureteric epithelium. We demonstrate that sonic hedgehog is expressed in the ureteric epithelium of the distal, non-branching medullary collecting ducts and...

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Identifiers

PMID: 12399320
DOI: 10.1242/dev.129.22.5301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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