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Article

mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils.

The Journal of clinical investigation - 1 Oct 2002

Staudinger Benjamin J, Oberdoerster Michele A, Lewis Patrick J, Rosen Henry

Abstract excerpt

To gain a better understanding of bacterial responses to complex and hostile environments generated within the neutrophil phagosome, we estimated mRNA abundance, using genomic arrays, in Escherichia coli cells ingested by normal and phagocyte oxidase-deficient human neutrophils. Genes regulated by the oxidant sensing transcription factor OxyR were among those strongly induced upon phagocytosis by normal, but not...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12393851
DOI: 10.1172/JCI15268
PMCID: PMC150791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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