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Article

Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas

30 Jan 2003

Abstract excerpt

Primary cutaneous lymphomas (PCLs) represent a heterogeneous group of extranodal T- and B-cell malignancies. The underlying molecular pathogenesis of this malignancy remains unclear. This study aimed to characterize oncogene abnormalities in PCLs. Using genomic microarray, we detected oncogene copy number gains of RAF1 (3p25), CTSB (8p22), PAK1 (11q13), and JUNB (19p13) in 5 of 7 cases of mycosis fungoides...

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Share to Cutaneous lymphoproliferative disorders research
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Identifiers

PMID: 12393503
DOI: 10.1182/blood-2002-08-2434

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