Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile

16 Dec 2002

Abstract excerpt

Genetic instability is a common feature in acute myeloid leukemia (AML). Centrosome aberrations have been described as a possible cause of aneuploidy in many human tumors. To investigate whether centrosome aberrations correlate with cytogenetic findings in AML, we examined a set of 51 AML samples by using a centrosome-specific antibody to pericentrin. All 51 AML samples analyzed displayed numerical and structural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer Genomics and Diagnostics
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12393441
DOI: 10.1182/blood-2002-04-1188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profilePMID 12393441Read ↗

Centrosome aberrations in hematological malignanciesSemantic proximity Read ↗

Origins and consequences of centrosome aberrations in human cancersSemantic proximity Read ↗

Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instabilitySemantic proximity Read ↗

Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issuesSemantic proximity Read ↗

A tentative classification of centrosome abnormalities in cancerSemantic proximity Read ↗

Centrosome – a promising anti-cancer targetSemantic proximity Read ↗

A catalog of numerical centrosome defects in epithelial ovarian cancersSemantic proximity Read ↗

Centrosome aberration accompanied with p53 mutation can induce genetic instability in hepatocellular carcinoma.Semantic proximity Read ↗

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness.Semantic proximity Read ↗

Centrosome amplification drives chromosomal instability in breast tumor development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.