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Article

Defective neurite outgrowth in aphidicolin/cAMP-induced motor neurons expressing mutant Cu/Zn superoxide dismutase.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Oct 2002

Lee Kwang-Woo, Kim Hyun-Jeong, Sung Jung-Joon, Park Kyung-Seok, Kim Manho

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by motor neuron involvement. Mutations in the human Cu/Zn superoxide dismutase (SOD1) gene are found in some cases of familial ALS. Many studies have reported SOD1 mutation-related neurodegeneration. However, whether or not a mutant SOD1 affects neural development has not been demonstrated. We developed motor...

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Source

Identifiers

PMID: 12392756
DOI: 10.1016/s0736-5748(02)00052-7

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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