Article
[Detection and analysis of Fas gene (exon 1-6) mutations in keloids].
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA - 1 Jan 2002
Liu Yong-Bo, Gao Jian-Hua, Duan Hong-Jie
Abstract excerpt
OBJECTIVE: To detect Fas DNA mutations (exon 1-6) in the fibroblasts of patients with keloids, thereby to understand the clinicopathological implications of altered structure of the keloids. METHODS: PCR followed by single-strand conformational polymorphism analysis and direct DNA sequencing were used to detect Fas gene mutations in 15 patients with keloids. RESULTS: Insertion and point mutations were identified...
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