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Article

No influence of 5-HTTLPR gene polymorphism on migraine symptomatology, comorbid depression, and chronification.

Headache - 1 Mar 2010

Wieser Thomas, Dresler Kathrin, Evers Stefan, Gaul Charly, König Dorothea, Hölzl Daniela, Berger Klaus, Nyholt Dale, Deufel Thomas

Abstract excerpt

BACKGROUND: The serotonergic system is thought to play an important role for mediating susceptibility to migraine and depression, which is frequently found comorbid in migraine. The functional polymorphism in the serotonin transporter gene linked polymorphic region (5-HTTLPR/SLC6A4) was previously associated with attack frequency and, thus, possibly with chronification. OBJECTIVE: We hypothesized that patients...

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Identifiers

PMID: 19438736
DOI: 10.1111/j.1526-4610.2009.01428.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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