Article
Increase in power of transmission-disequilibrium tests for quantitative traits.
Genetic epidemiology - 1 Oct 2002
Malkin Ida, Ginsburg Emil, Elston Robert C
Abstract excerpt
Allison ([1997] Am. J. Hum. Genet. 60:676-690) proposed four versions of the transmission-disequilibrium test (TDT) for quantitative traits when there is extreme-threshold sampling, i.e., the trios having an offspring trait value between a priori defined thresholds are excluded from the analysis. Keeping intact the ideology and construction of these tests, we propose here an extreme-offspring design for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
