Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.

BMC cancer - 17 Oct 2002

Mahyar-Roemer Mojgan, Köhler Hans, Roemer Klaus

Abstract excerpt

BACKGROUND: The natural plant polyphenol resveratrol present in some foods including grapes, wine, and peanuts, has been implicated in the inhibition, delay, and reversion of cellular events associated with heart diseases and tumorigenesis. Recent work has suggested that the cancer chemoprotective effect of the compound is primarily linked to its ability to induce cell division cycle arrest and apoptosis, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Resveratrol
Share to Proto-Oncogene Proteins c-bcl-2
Share to Anticarcinogenic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to bcl-2-Associated X Protein

Share to Carcinoma

Share to Cell Survival

Share to Membrane Potentials

Share to Stilbenes

Source

Open in PubMed Open full text

Identifiers

PMID: 12383351
DOI: 10.1186/1471-2407-2-27
PMCID: PMC130964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.PMID 12383351Read ↗

Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapseSemantic proximity Read ↗

Role of BAX in the apoptotic response to anticancer agents.Semantic proximity Read ↗

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.Semantic proximity Read ↗

Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells.Semantic proximity Read ↗

Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.Semantic proximity Read ↗

A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.Semantic proximity Read ↗

HS-1793, a resveratrol analogue, induces cell cycle arrest and apoptotic cell death in human breast cancer cellsSemantic proximity Read ↗

Cytotoxic Effect of Resveratrol on Colorectal Cancer Cell LineSemantic proximity Read ↗

The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer modelsSemantic proximity Read ↗

Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanismSemantic proximity Read ↗

Anti-cancer Effects of JKA97 Are Associated with Its Induction of Cell Apoptosis via a Bax-dependent and p53-independent PathwaySemantic proximity Read ↗

Oncogenic KRAS mutations modulate BAX-mediated cell death.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.