Article
Virulence of Candida albicans mutants toward larval Galleria mellonella (Insecta, Lepidoptera, Galleridae).
Canadian journal of microbiology - 1 Aug 2003
Dunphy Gary B, Oberholzer Ursula, Whiteway Malcolm, Zakarian Robert J, Boomer Iian
Abstract excerpt
Culture medium affected the virulence of a strain of Candida albicans toward Galleria mellonella larvae, but the yeast growth rates in yeast extract - peptone - dextrose broth and synthetic Galleria serum were not correlated with yeast virulence. Virulent C. albicans grew rapidly in larval serum, whereas, it limited nodulation and continued development in vivo, producing toxins that damaged the hemocytes and fat...
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