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Acquisition of Mn(II) in Addition to Fe(II) Is Required for Full Virulence of <i>Salmonella enterica</i> Serovar Typhimurium

15 Oct 2002

Abstract excerpt

The roles of the genes feoB (ABC ferrous iron transporter), mntH (proton-dependent manganese transporter), and sitABCD (putative ABC iron and/or manganese transporter) in Salmonella pathogenicity were investigated by using mutant strains deficient in one, two, or three transporters. Our results indicated that sitABCD encodes an important transporter of Mn(II) and Fe(II) which is required for full virulence in...

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PMID: 12379679
DOI: 10.1128/iai.70.11.6032-6042.2002

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