Article
Kinetic analysis of GTP hydrolysis catalysed by the Arf1-GTP-ASAP1 complex.
The Biochemical journal - 15 Mar 2007
Luo Ruibai, Ahvazi Bijan, Amariei Diana, Shroder Deborah, Burrola Beatriz, Losert Wolfgang, Randazzo Paul A
Abstract excerpt
Arf (ADP-ribosylation factor) GAPs (GTPase-activating proteins) are enzymes that catalyse the hydrolysis of GTP bound to the small GTP-binding protein Arf. They have also been proposed to function as Arf effectors and oncogenes. We have set out to characterize the kinetics of the GAP-induced GTP...
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