Article
Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies.
Nutrition reviews - 1 Oct 2013
Zambrano Elena, Nathanielsz Peter W
Abstract excerpt
Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and metabolic disease. Carefully controlled studies in precocial and altricial mammalian species provide insights into the involved mechanisms. These include programming of hypothalamic appetite-regulating centers to increase orexigenic relative to anorexigenic drive; increasing maternal, fetal, and offspring adrenal and...
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