Article
[The relationship of aldosterone synthase gene polymorphism with hypertension and left ventricular hypertrophy].
Zhonghua nei ke za zhi - 1 May 2002
Chen Aihua, Zhang Wenxiu, Tang Xiaoming, Li Zhiliang, Lu Qing, Qian Xuexian
Abstract excerpt
OBJECTIVE: To investigate the relationship of gene polymorphism of angiotension converting enzyme (ACE), aldosterone synthase (CYP11B2) with essential hypertension (EH) and left ventricular hypertrophy (LVH) in hypertensive patients. METHODS: (1) Left ventricular mass and geometry were assessed with ECG and echocardiography in 136 hypertensive patients. (2) The insertion/deletion polymorphism of ACE gene and the...
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