Article
BRCA2 gene mutations in families with aggregations of breast and stomach cancers.
British journal of cancer - 7 Oct 2002
Jakubowska A, Nej K, Huzarski T, Scott R J, Lubiński J
Abstract excerpt
Stomach cancer ranks second to lung cancer in the global cancer burden. It is estimated that 25% of families meeting the criteria for hereditary diffuse gastric carcinoma (HDCG) will have germline mutations in the E-cadherin gene. Evidence suggests that stomach cancer might also be a malignant manifestation of other inherited predispositions to disease. Recently, it has been reported that the incidence of stomach...
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