Article
GATA2 gene analysis in several forms of hematological malignancies including familial aggregations.
Annals of hematology - 1 Oct 2017
Hamadou Walid Sabri, Mani Rahma, Besbes Sawsen, Bourdon Violaine, Youssef Yosra Ben, Eisinger François, Mari Véronique, Gesta Paul, Dreyfus Hélène, Bonadona Valérie, Dugast Catherine, Zattara Hélène, Faivre Laurence, Noguchi Testsuro, Khélif Abderrahim, Sobol Hagay, Soua Zohra
Abstract excerpt
The genetic predisposition to familial hematological malignancies has been previously reported highlighting inherited gene mutations. Several genes have been reported but genetic basis remains not well defined. In this study, we extended our investigation to a potential candidate GATA2 gene which was analyzed by direct sequencing in 119 cases including familial aggregations with a variety of hematological...
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