Article
Association of sporadic and familial Barrett's esophagus with breast cancer.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Apr 2018
Chan M Q, Blum A E, Chandar A K, Emmons A M L Kieber, Shindo Y, Brock W, Falk G W, Canto M I, Wang J S, Iyer P G, Shaheen N J, Grady W M, Abrams J A, Thota P N, Guda K K, Chak A
Abstract excerpt
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC). Based on striking aggregation of breast cancer and BE/EAC within families as well as shared risk factors and molecular mechanisms of carcinogenesis, we hypothesized that BE may be associated with breast cancer. Pedigree analysis of families identified prospectively at multiple academic centers as part of the Familial...
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