Article
MTV1 and MTV4 encode plant-specific ENTH and ARF GAP proteins that mediate clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network.
The Plant cell - 1 Jun 2013
Sauer Michael, Delgadillo M Otilia, Zouhar Jan, Reynolds Gregory D, Pennington Janice G, Jiang Liwen, Liljegren Sarah J, Stierhof York-Dieter, De Jaeger Geert, Otegui Marisa S, Bednarek Sebastian Y, Rojo Enrique
Abstract excerpt
Many soluble proteins transit through the trans-Golgi network (TGN) and the prevacuolar compartment (PVC) en route to the vacuole, but our mechanistic understanding of this vectorial trafficking step in plants is limited. In particular, it is unknown whether clathrin-coated vesicles (CCVs) participate in this transport step. Through a screen for modified transport to the vacuole (mtv) mutants that secrete the...
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