Article
The impact of apoptosis and inflammation gene polymorphisms on transplanted kidney function.
Annals of transplantation - 4 Jun 2013
La Manna Gaetano, Cappuccilli Maria L, Capelli Irene, Baraldi Olga, Cuna Vania, Battaglino Giuseppe, Feliciangeli Giorgio, Dormi Ada, Scolari Maria P, Stefoni Sergio
Abstract excerpt
BACKGROUND: The progressive deterioration of kidney allograft function leads in most cases to transplant failure. Polymorphisms in genes encoding for inflammatory and apoptosis molecules may be one possible explanation for interindividual differences in kidney transplant outcomes. The objective of our work was to identify the possible effect of interleukin 6 (IL-6), transforming growth factor beta 1 (TGFB1), and...
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