Article
The association between cytokine gene polymorphisms and kidney allograft survival.
Annals of transplantation - 1 Jan 2008
Pawlik Andrzej, Domanski Leszek, Rozanski Jacek, Czerny Bogusław, Juzyszyn Zygmunt, Dutkiewicz Grazyna, Myslak Marek, Hałasa Maciej, Słojewski Marcin, Dabrowska-Zamojcin Ewa
Abstract excerpt
BACKGROUND: Cytokines regulate cellular and humoral immune responses. One determinant of the variable cytokine production observed among individuals is genetic polymorphism in cytokine genes. These polymorphisms represent normal allelic variations in the cytokine genes; usually single base changes. Homozygous genotypes for high producer alleles are generally associated with high cytokine production, heterozygotes...
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