Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthesis and study of a gramicidin B mutant possessing a ditryptophan crosslink.

Journal of peptide science : an official publication of the European Peptide Society - 1 Sept 2002

Presley Bodnar Alice L, Gilbert Eric J, Yoburn Joshua C, Van Vranken David L

Abstract excerpt

Recent studies of peptide dimers linked by Trp-Trp (ditryptophan) crosslinks suggest that the crosslinks can reinforce antiparallel beta-structure. Depending on environment, gramicidins A, B and C form either helical ion channels with parallel beta-structure or non-functional pores with antiparallel beta-structure. In the channel conformation of the gramicidins Trp9 and Trp15 are close in space, but in the pore...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacteria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circular Dichroism

Share to Cross-Linking Reagents

Share to Mutation

Share to Photochemistry

Share to Protein Conformation

Share to Tryptophan

Source

Identifiers

PMID: 12371704
DOI: 10.1002/psc.417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Synthesis and study of a gramicidin B mutant possessing a ditryptophan crosslink.PMID 12371704Read ↗

Design and characterization of gramicidin channels with side chain or backbone mutations.Semantic proximity Read ↗

Chemical and photochemical modification of colicin E1 and gramicidin A in bilayer lipid membranes.Semantic proximity Read ↗

The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores.Semantic proximity Read ↗

Crucial role of H322 in folding of the diphtheria toxin T-domain into the open-channel state.Semantic proximity Read ↗

Interactions between subunits a and b in the rotary ATP synthase as determined by cross-linking.Semantic proximity Read ↗

Intersubunit crosslinking of the heterotetrameric proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli defines intersubunit contacts between transmembrane helices of the beta subunits.Semantic proximity Read ↗

Effect of streptavidins with varying biotin binding affinities on the properties of biotinylated gramicidin channels.Semantic proximity Read ↗

Photoinduced transformation of UVR8 monitored by vibrational and fluorescence spectroscopy.Semantic proximity Read ↗

Probing the structure of the dimeric KtrB membrane protein.Semantic proximity Read ↗

Structural features and activity of Brazzein and its mutants upon substitution of a surfaced exposed alanine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.