Article
Probing the structure of the dimeric KtrB membrane protein.
The Journal of biological chemistry - 30 Nov 2007
Albright Ronald A, Joh Kyu, Morais-Cabral João H
Abstract excerpt
The KtrAB ion transporter is a complex of two proteins, KtrB and KtrA. The integral membrane protein KtrB is expected to adopt the structural architecture typified by the pore domain of potassium channels. Here we show that homo-dimerization of KtrB proteins is most likely a general property of this family of transporters. Using cysteine mutants and bifunctional cross-linkers we define regions of the Bacillus...
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