Article
High-resolution mapping of changes in histone-DNA contacts of nucleosomes remodeled by ISW2.
Molecular and cellular biology - 1 Nov 2002
Kassabov Stefan R, Henry Nathalia M, Zofall Martin, Tsukiyama Toshio, Bartholomew Blaine
Abstract excerpt
The imitation switch (ISWI) complex from yeast containing the Isw2 and Itc1 proteins was shown to preferentially slide mononucleosomes with as little as 23 bp of linker DNA from the end to the center of DNA. The contacts of unique residues in the histone fold regions of H4, H2B, and H2A with DNA were determined with base pair resolution before and after chromatin remodeling by a site-specific photochemical...
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