Article

Gene fitness landscape of group A streptococcus during necrotizing myositis

2018-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Necrotizing fasciitis and myositis are devastating infections characterized by high mortality. Group A streptococcus (GAS) is a common cause of these infections, but the molecular pathogenesis is poorly understood. We report a genome-wide analysis using serotype M1 and M28 strains that identified novel GAS genes contributing to necrotizing myositis in nonhuman primates (NHP), a clinically releva...

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Literature Corpus work: 761b4f64-719d-5ee1-847a-6c5ec9aacca3
DOI: 10.1101/432526

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