Article
Allelic heterogeneity of HLA-B35 subtypes in different populations as assessed by DNA typing.
Tissue antigens - 1 Sept 1995
Satz M L, Fernández-Viña M, Theiler G C, Marcos Y C, Lindel N, Capucchio M, Gorodezky C, Fainboim L, Stastny P
Abstract excerpt
HLA-B35, a class I antigen differentially associated to several diseases in different ethnic groups, comprises at least eight alleles which differ among them by one to six amino acids. In the present work a rapid DNA typing procedure was used to investigate the distribution of the various HLA-B35 alleles in different populations. The approach is based on a group-specific PCR amplification of a set of closely...
Topics
- Alleles
- Base Sequence
- DNA Primers
- Genes, MHC Class I
- HLA-B35 Antigen
- Histocompatibility Testing
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
