Article
p53 mutations as tumor markers in fine needle aspirates of palpable breast masses.
Acta cytologica - 1 Jan 2000
Dillon Deborah A, Hipolito Emanuel, Zheng Karl, Rimm David L, Costa José C
Abstract excerpt
OBJECTIVE: Mutations in p53 exons 5-8 are found in 40-50% of breast carcinomas. We performed a retrospective analysis of p53 mutations in fluid-based, archival fine needle aspirates (FNAs) of breast masses to determine their potential diagnostic utility as breast tumor cell markers. STUDY DESIGN: Residual, fluid-based, archival FNAs of 27 breast masses were retrospectively evaluated by polymerase chain reaction...
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