Article
Astral microtubules monitor metaphase spindle alignment in fission yeast.
Nature cell biology - 1 Oct 2002
Oliferenko Snezhana, Balasubramanian Mohan K
Abstract excerpt
Segregating genetic material along the longest axis of the cell ensures that there is a sufficient distance between daughter chromosomes at the point of cytokinesis. Monitoring the orientation of the mitotic spindle can be subjected to cell cycle controls. In the fission yeast Schizosaccharomyces pombe, the existence of such a cell-cycle checkpoint has been proposed to delay the metaphase to anaphase transition...
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