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Article

The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins.

The Journal of biological chemistry - 20 Dec 2002

Dell Edward J, Connor Jennifer, Chen Songhai, Stebbins Elizabeth G, Skiba Nikolai P, Mochly-Rosen Daria, Hamm Heidi E

Abstract excerpt

A yeast two-hybrid approach was used to discern possible new effectors for the betagamma subunit of heterotrimeric G proteins. Three of the clones isolated are structurally similar to Gbeta, each exhibiting the WD40 repeat motif. Two of these proteins, the receptor for activated C kinase 1 (RACK1) and the dynein intermediate chain, co-immunoprecipitate with Gbetagamma using an anti-Gbeta antibody. The third...

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Identifiers

PMID: 12359736
DOI: 10.1074/jbc.M202755200

Genes

RACK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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