Article
Interleukin-6 gene promoter-572 C allele may play a role in rate of disease progression in multiple sclerosis.
International journal of molecular sciences - 22 Oct 2012
Yan Jun, Liu Jia, Lin Clement Yihao, Csurhes Peter A, Pender Michael P, McCombe Pamela A, Greer Judith M
Abstract excerpt
Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system. Although the exact pathogenesis of MS is unknown, it is generally considered to be an autoimmune disease, with numerous genetic and environmental factors determining disease susceptibility and severity. One important mediator of immune responses and inflammation is interleukin-6 (IL-6). Previously, elevated...
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