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Article

Limits of isolation and culture: intact vascular endothelium and BK Ca

1 May 2009

Abstract excerpt

The potential physiological role of plasmalemmal large-conductance calcium-activated potassium channels (BK(Ca)) in vascular endothelial cells is controversial. Studies of freshly isolated and cultured vascular endothelial cells provide disparate results, both supporting and refuting a role for BK(Ca) in endothelial function. Most studies using freshly isolated, intact, healthy arteries provide little support for...

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PMID: 19411289
DOI: 10.1152/ajpheart.00042.2009

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