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Article

Role of the sterol carrier protein-2 N-terminal membrane binding domain in sterol transfer.

Biochemistry - 8 Oct 2002

Huang Huan, Gallegos Adalberto M, Zhou Minglong, Ball Judith M, Schroeder Friedhelm

Abstract excerpt

Previous studies showed that the N-terminal 32 amino acids of sterol carrier protein-2 ((1-32)SCP(2)) comprise an amphipathic alpha-helix essential for SCP(2) binding to membranes [Huang et al. (1999) Biochemistry 38, 13231]. However, it is unclear whether membrane interaction of the (1-32)SCP(2) portion of SCP(2) is in itself sufficient to mediate intermembrane sterol transfer, possibly by altering membrane...

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Identifiers

PMID: 12356316
DOI: 10.1021/bi0260536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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