Article
Effects of mutations in Aedes aegypti sterol carrier protein-2 on the biological function of the protein.
Biochemistry - 7 Sept 2010
Radek James T, Dyer David H, Lan Que
Abstract excerpt
Sterol carrier protein-2 (SCP-2) is a nonspecific intracellular lipid carrier protein. However, the molecular mechanism of ligand selectivity and the in vivo function of SCP-2 remain unclear. In this study, we used site-directed mutagenesis to investigate the ligand selectivity and in vivo function of the yellow fever mosquito sterol carrier protein-2 protein (AeSCP-2). Mutations to amino acids in AeSCP-2 known...
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